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KMID : 0372919820030010003
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Journal of Biomedical Engineering Research
1982 Volume.3 No. 1 p.3 ~ p.8
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Effect of Ultrafiltration on the Clearance of Artificial Kidney Dialyzers
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Abstract
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Solute transfer in artificial kidney dialyzers was analyzed using Kedem-Katcha- Isky’’’’s description on membrane transport. Mass transfer coefficient, K was deduced from the diffusive clearance of commercial hemodialyzers. It can to seen that Kd increases with the increase of blood flow rate, which means that there is substantial resistance in the blood phase for solute transport. Total clearance was estimated with the Werynski’’’’s formula. The increase in total clearance due to ultrafiltration was most significant for middle molecules like vitamin Bla, however that for smaller molecules such as urea and creatinine was minimal.
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